Edecrin Sodium
Ethacrynate Sodium
CAS: 6500-81-8
Molecular Formula: C13H11Cl2NaO4
Edecrin Sodium - Names and Identifiers
Edecrin Sodium - Physico-chemical Properties
| Molecular Formula | C13H11Cl2NaO4 |
| Molar Mass | 325.12 |
| Boling Point | 480°C at 760 mmHg |
| Flash Point | 244.1°C |
| Vapor Presure | 5.04E-10mmHg at 25°C |
Edecrin Sodium - Standard
Authoritative Data Verified Data
This product is sodium [2, 3-dichloro-4-(2-methylenebutyryl) phenoxy] acetate. Calculated as dry product, containing no less than 98.0% of C13H11Cl2Na04.
Last Update：2024-01-02 23:10:35
Edecrin Sodium - Trait
Authoritative Data Verified Data
- This product is white powder; Odorless.
- This product is soluble in water and slightly soluble in ethanol.
Last Update：2022-01-01 13:35:55
Edecrin Sodium - Differential diagnosis
Authoritative Data Verified Data
- taking this product, according to the identification (1) and (4) tests under the item of etanoic acid, the same reaction was shown.
- The infrared absorption spectrum of this product should be consistent with that of the control (Spectrum set 197).
- identification reaction of sodium salt of this product (General rule 0301).
Last Update：2022-01-01 13:35:55
Edecrin Sodium - Exam
Authoritative Data Verified Data
acidity
take 25mg of this product, add 25ml of water to dissolve, and then measure it according to law (General rule 0631). The pH value should be 5.5~7.0.
loss on drying
take this product, with phosphorus pentoxide as desiccant, at 60°C under reduced pressure drying to constant weight, weight loss should not exceed 4.0% (General rule 0831).
Heavy metals
This product l.Og, inspection according to law (General Principles 0821 second law), containing heavy metals shall not exceed 20 parts per million.
sterile
take this product, dissolve and dilute with appropriate solvent, after membrane filtration treatment, inspection according to law (General rule 1101), should comply with the provisions.
Last Update：2022-01-01 13:35:56
Edecrin Sodium - Content determination
Authoritative Data Verified Data
take this product about 0.15g, precision weighing, according to the method of etanoic acid under. Each 1 ml of bromine titration solution (0.05mol/L) corresponds to 16.26mg of C13H11Cl2Na04.
Last Update：2022-01-01 13:35:56
Edecrin Sodium - Category
Authoritative Data Verified Data
diuretics.
Last Update：2022-01-01 13:35:57
Edecrin Sodium - Storage
Authoritative Data Verified Data
under shading, sealed and preserved.
Last Update：2022-01-01 13:35:57
Edecrin Sodium - Etanercose sodium for injection
Authoritative Data Verified Data
This product is the sterilized powder of etanercate sodium. Based on the average loading, the content of etanercate sodium (C13H11Cl2Na04) shall be 90.0% to 110.0% of the labeled amount.
trait
This product is white powder; Odorless.
identification
take this product, according to the identification test under the item of etanercate sodium, show the same reaction.
examination
- acidity: take 25mg of this product, add 25ml of water to dissolve it, and then measure it according to law (General rule 0631). The pH value should be 5.5~7.0.
- weight loss on drying: take this product with phosphorus pentoxide as desiccant, and dry under reduced pressure at 60°C to constant weight. The weight loss shall not exceed 5.0% (General rule 0831).
- sterile take this product, dissolve and dilute with a suitable solvent to prepare a solution containing lOmg per lml, and treat it by membrane filtration method, and check it according to law (General rule 1101).
- others should comply with the relevant provisions under injection (General 0102).
Content determination
The contents under the item of difference in loading were collected, mixed uniformly, and about 0.15g was accurately weighed and measured according to the method under the item of etanoic acid. Each 1 ml of bromine titration solution (0.05mol/L) corresponds to 16.26mg of C13H11Cl2Na04.
category
etanolate sodium
specification
25mg
storage
light shielding, closed storage.
Last Update：2022-01-01 13:35:57
Edecrin Sodium - Reference Information
| biological activity | ethacacrynic acid Sodium is the sodium salt form of ethacacrynic acid. Ethacrynic acid can inhibit the transfer of sodium ion, potassium ion and chloride ion, mainly in the ascending branch of the thin wall segment of the medullary loop, and also acts on the distal and proximal tubules. |
Last Update：2024-04-10 22:29:15
